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DDD85646 (IMP-366) is a research-grade small-molecule inhibitor of N-myristoyltransferase (NMT) with low-nanomolar activity against Trypanosoma brucei and human NMT. It is supplied with purity documentation and is intended for laboratory research use only.
Low-nanomolar potency against TbNMT and hNMT (reported IC50s ~2 nM and ~4 nM)
Available as solid or 10 mM solutions in DMSO for immediate use
High reported purity (≈99.7%) with accompanying documentation
Provided in multiple solid package sizes to support screening and scale-up
Suitable for biochemical assays and cell-based NMT research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
NVR 3-778 is a first-in-class, orally bioavailable hepatitis B virus (HBV) capsid assembly modulator (CAM) of the sulfamoylbenzamide chemical class used in research to inhibit HBV replication and the generation of infectious viral particles. It has been characterized in preclinical and clinical studies and is supplied for research use with high reported purity and defined physicochemical properties.
First-in-class capsid assembly modulator with demonstrated antiviral activity.
Orally bioavailable small molecule suitable for preclinical assays.
Pan-genotypic inhibition of HBV replication in cell-based models.
Solid, white to off-white material with reported solubility in DMSO and ethanol.
High reported purity appropriate for research applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
VLX600 is an iron-chelating inhibitor of oxidative phosphorylation used as a research tool to induce mitochondrial dysfunction, shift cellular metabolism toward glycolysis, and trigger autophagy and selective cytotoxicity in malignant cells. It is supplied for research use and is characterized by CAS 327031-55-0, molecular formula C17H15N7, and molecular weight 317.35 g/mol.
Iron-chelating inhibitor of oxidative phosphorylation that disrupts mitochondrial function.
Induces a metabolic shift toward glycolysis in treated cells.
Promotes autophagy and selective cytotoxicity in malignant or quiescent cancer cells.
High chemical purity, typically 99.8%.
Supplied in small pack sizes suitable for in vitro research (for example, 10 mg).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Gallic acid (CAS 149-91-7) is a naturally occurring polyphenolic compound widely distributed in the plant kingdom with substantial levels identified in sources such as gallnuts grapes tea hops and oak bark It exerts biological effects primarily through antioxidant and anti-inflammatory mechanisms including scavenging free radicals and modulating cellular oxidative stress pathways Gallic acid has been investigated for its capacity to inhibit enzymes involved in inflammation and carcinogenesis influencing cell proliferation and apoptosis in various in vitro models Due to these properties it serves as a valuable tool for studies on oxidative damage inflammation and cancer biology
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More